
Biotec Pharmacon is specializing in DNA-modifying enzymes. Marine organisms living in Arctic waters have become adapted to low temperatures and, unlike in warm-blooded animals, their enzymes and various physiological processes are fully functional down to the freezing point of water. Cold adapted organisms therefore are sources of enzymes with other properties and commercial potentials than corresponding enzymes from other biological sources.
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Arctic Surroundings |
Actual advantages are:
Heat lability: In many applications there is a need to remove enzyme activity after the enzyme catalysed reaction is completed. For cold-adapted enzymes this is easy - because they have a very useful "off-switch". Simply by raising the temperature by 20-40 degrees, cold adapted enzymes may be rapidly inactivated, unlike enzymes from organisms living at higher temperatures.
High processivity: Cold-adapted enzymes often show a higher catalytic efficiency, either by higher substrate affinity (lower Km) and/or increased turnover (kcat).
Lower temperature optimum: At ambient to low temperatures, much less enzyme (1/5 to 1/2) may be required to obtain the same reaction rate.
Quality:
Our enzymes are highly purified to provide the quality required for their use. Each product has been tested for critical contaminants, and no additional purification is necessary.
Products: